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2007/4/1

Competitor for Diet Drug Rimonabant (Acomplia) Now Has Name: Taranabant

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@ 11:18 PM (20 months, 1 day ago)

While Sanofi's diet drug Rimonabant (Acomplia / Zimulti) remains stalled at the FDA, a potential competitor currently in phase III trials, Merck's MK-0364, now has an official generic name: Taranabant.

Taranabant is Merck's cannabinoid-1 (CB-1) receptor inverse agonist, and from reports we periodically receive from participants in the phase III trial of this diet drug, taranabant is as effective for weight loss as rimonabant with fewer side effects.

While Merck has not reported interim results from the phase III trial, which obviously could prove different from the anecdotal reports we receive, the company has said the pill was well tolerated in extensive phase II trials and that it plans to seek FDA approval for Taranabant next year.

Meanwhile Pfizer, which also has a CB-1 receptor antagonist in phase III trials, has as of yet not moved forward with a name for the diet drug known only as CP-945598.

Merck and Pfizer both will be watching intently the coming June FDA advisory panel meeting on rimonabant, which is expected to focus heavily on safety issues associated with this novel class of drugs that affect receptors in the brain.

Source: http://www.acompliareport.com/

Comment(s) »

  1. I want to hear others in this study! I am sure this drug is a winner....I have been taking it for 5 months!

    Comment by rose— 2007/04/14 @ 05:30 PM — (Reply)

  2. Rose,
    Have you been taking the Acomplia or the Merck trial? You weren't specific. Are you in the US? I am interested in this product. I was a Redux user and found success with Redux. How much did you have to loose and how much have you lost? Did you use Redux?
    Tammie

    Comment by Tammie— 2007/05/15 @ 06:55 AM — (Reply)

  3. Tammy,
    I have been taking Merck Mk-0364 on a trial basis. I have lost about 45 pounds in 6 months. I really think this is a great drug. Very few side effects that I can see! Let me know more about your Redux! If you want more info...email me at craftdata@aol.com.
    Hope to hear from you!

    Comment by — 2007/06/06 @ 07:35 AM — (Reply)

  4. Tammy,
    I have been taking Merck Mk-0364 on a trial basis. I have lost about 45 pounds in 6 months. I really think this is a great drug. Very few side effects that I can see! Let me know more about your Redux! If you want more info...email me at craftdata@aol.com.
    Hope to hear from you!

    Comment by — 2007/06/06 @ 07:35 AM — (Reply)

  5. I am interested in buying Rimonabant. What website can I do this?
    Thanks,
    Sally

    Comment by Sally— 2007/07/17 @ 06:14 PM — (Reply)

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